A wrinkle is a fold, ridge or crease in the skin. Skin wrinkles typically appear as a result of aging processes such as glycation or, temporarily, as the result of prolonged (more than a few minutes) immersion in water. Wrinkling in the skin is caused by habitual facial expressions, aging, sun damage, smoking, poor hydration, and various other factors. With prolonged water exposure, the outer layer of skin starts to absorb water. The skin doesn't expand evenly, causing it to wrinkle. Depletion of water in the body, as occurs with dehydration, can also cause this puckering of the skin. Cortisol causes degradation of skin collagen.

Contents

• 1 Treatments for aging wrinkles
  • 1.1 Tretinoin
  • 1.2 Epidermal Growth Factor
  • 1.3 Glycosaminoglycans
  • 1.4 Dermal fillers
  • 1.5 Botulinum toxin
• 2 Water Aging
• 3 Animals with wrinkles
• 4 References
• 5 External links

Treatments for aging wrinkles

Noun

wrinkle (plural wrinkles)

1. A small furrow, ridge or crease in an otherwise smooth surface.
2. A line or crease in the skin, especially when caused by age or fatigue.

   Spending time out in the sun may cause you to develop wrinkles sooner.

3. A fault, imperfection or bug especially in a new system or product; typically, they will need to be ironed out.

   Three months later, we're still discovering new wrinkles.

Verb

wrinkle (third-person singular simple present wrinkles, present participle wrinkling, simple past and past participle wrinkled)

1. (transitive) To make wrinkles in; to cause to have wrinkles.

   Be careful not to wrinkle your dress before we arrive.

2. (intransitive) To pucker or become uneven or irregular.

   An hour in the tub will cause your fingers to wrinkle.

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See also:

• Health: Aging: Anti-Aging (31)
• Shopping: Health: Alternative: Life Extension (53)
• Shopping: Health: Alternative: Life Extension: Human Growth Hormone (25)

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• Colladerm
  colladerm.com
  Moisturizer based on soluble collagen, hydrolyzed elastin and allantoin. Claims to replenish skin's ingredients to help minimize the appearance of fine lines and wrinkles.
• Dinur Cosmetics
  dinur.net
  Skin care products for damaged skin.
• Nurturaa
  nurturaa.com
  Skin care products made from tropical botanicals grown in the Hawaiian Islands.